However, these effects are contingent on the delivery of GSH or its precursors to the necessary targets (Vzquez-Meza et al., 2023)
Observational human studies have reported the presence of MNPs in patients with myocardial infarctions, acute coronary syndrome, coronary artery disease, extracranial artery stenosis, and asymptomatic extracranial internal carotid artery stenosis, where higher MNP levels have been associated with inflammatory and coagulation-related biomarkers and disease severity
This strategy is the basis for many anticancer therapeutics, including chemotherapeutics, radiotherapies, and most small-molecule inhibitor-based therapies, which impair tumor metabolism and induce excessive ROS accumulation, inducing cell toxicity and death
Choi, K.-C., Kim, S.-H., Ha, J.-Y., Kim, S.-T