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The GWAS was performed including covariates as described in equation 1 above, with the addition of five genetic principal components to account for fine-scale genetic ancestry, and indicator variables to account for variation in the genotyping platform

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A gradual taper or dose reduction, rather than stopping abruptly, may help your body adjust

Researchers should select based on the dominant biology of their atrophy or hypertrophy model, with mechanistic controls (wortmannin/rapamycin versus JA16/SB-431542) essential to attribute observed phenotypes to the correct pathway.