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Keywords: autoimmune diseases, DPP4 inhibitors, inflammatory disorders, MERS-CoV, diabetes mellitus, COVID-19 Introduction Dipeptidyl-peptidase 4 (DPP4), also known as CD26, is a significant enzyme belonging to the SC serine peptidase clan, specifically within its subfamily 9b

But they transformed a peptide with a 20-minute half-life into one that circulates for 20 to 30 hours

This, according to Parnacott, is largely due to its dual-action mechanism. Developing a medication that targets two distinct pathways in the body required a more complex production process, extensive clinical trials, and significant research investments, he explains