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Pu J, Wang Q, Xu W, Lu L, Jiang S
Alternatively, pharmacological targeting of other players in the LE/Lys compartment that are intimately linked to Rab7 activity, including the mammalian target of rapamycin and vacuolar-type ATPase, or capable of modifying Rab7 activity through phosphorylation, palmitoylation and ubiquitination, could offer therapeutic opportunities [80, 81]
Secondly, unlike reviews focusing solely on ovulation, we specifically elucidate how these systemic metabolicmicrobial disturbances converge to disrupt the endometrial window of implantation via specific oxidative pathways (e.g., mitochondrial dysfunction and ferroptosis)