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*Correspondence: Hui Chen [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Long-term LAC can significantly reduce the GABA level in the hippocampus of mice, but the GABA level in the cortex did not change significantly (103)

This may indicate inadequate nutrition, an underlying medical condition, or a need for treatment modification