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Specifically, GLP-1 receptors are enriched in the lateral septum (where expression is highest), hypothalamus, amygdala, bed nucleus of the stria terminalis, hippocampus, ventral tegmental area (VTA), and nucleus accumbens (NAc)
GLP-1 receptor agonist medications, including semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro), can be injected into the upper arm as an approved subcutaneous injection site
The most commonly reported side effects of topical peptide application are mild scalp irritation or redness, which typically resolves within a few days
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