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After opening, refrigerate it and use within its preservative window (commonly cited around 28 days)

Research with mice shows that relatively large doses of Vitamin C not only prevent the otherwise inevitable cellular damage of an induced Glutathione deficiency, but the Vitamin C also raised Glutathione levels inside the cell

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Further studies in Per2Luc knock-in mice revealed that chronic light-dark disruption elevated pro-inflammatory cytokines (e.g., IL1, IL6, GM-CSF) and impaired host resilience to endotoxin challenge 126