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Phase 2 trial data (Jastreboff et al., NEJM, 2023) showed mean body weight reductions of approximately 24% at 48 weeks with the highest dose, with no clear plateau observed

These differences matter because access challenges, such as refill difficulty and medication switching, show up across every care pathway, suggesting that no single model has solved the problem of continuity

Always check the most recent version of your plans formulary or contact your insurance plan directly to determine coverage options

Some Reddit users express worry and even panic about the possible effects of the medication on their early pregnancy