(11) Research models of GH deficiencies were examined in the course of this controlled study, where rhIGF-1 was presented once daily to all the models
van Leiden HA, Dekker JM, Moll AC, Nijpels G, Heine RJ, Bouter LM,
10.1371/journal.pone.0078434 34 ClaesS
Methods Eligibility criteria The PICOS strategy was defined as follows: P (participants) human subjects, I (interventions) oral LC treatment, C (comparisons) between supplementation and placebo, supplementation and control, or pre- and post- supplementation, O (outcomes) muscle variables, and S (study design) randomized controlled trials, non-randomized controlled trials, non-randomized non-controlled trials