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[57] This biochemical cascade increases mitochondrial thermogenesis, effectively forcing the body to dissipate excess calories as heat and increasing overall energy expenditure

This results in increased lean muscle mass and improved recovery times

Indeed, it has been suggested that certain cytokines that are upregulated during HIV infection have the capacity to induce the production of -MSH by oral melanocytes and keratinocytes and to mediate the upregulation of expression of MC1R by melanocytes, resulting in increased melanin production

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