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Additionally, by phosphorylating p62, mTORC1 facilitates the binding of p62 and Keap1, which causes Keap1 to degrade and NRF2 to accumulate (107)
2) This series of experiments completed by researchers Carvos et al systematically investigated the pharmacological effects, receptor dependence, and central mechanisms underlying cagrilintides anorectic and weight-lowering properties in mice
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