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Ibuprofen can exacerbate gastrointestinal symptoms by: Irritating the gastric mucosa NSAIDs reduce protective prostaglandins in the stomach lining Increasing ulcer risk particularly with prolonged use or higher doses Causing dyspepsia heartburn, indigestion, and upper abdominal discomfort Potentially worsening nausea adding to existing Wegovy-related symptoms Renal function considerations are also relevant
Early research suggests semaglutide may help improve insulin sensitivity and support weight loss, which in turn can restore more regular cycles and improve ovulation
2018 Oct 22;9:598
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