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Inflammatory cytokines blunt GLP-1 receptor responsiveness and destabilize insulin signaling, contributing to metabolic relapse
Hershman DL, Unger JM, Crew KD, Minasian LM, Awad D, Moinpour CM, Hansen L, Lew DL, Greenlee H, Fehrenbacher L, Wade JL 3rd, Wong SF, Hortobagyi GN, Meyskens FL, Albain KS
In a clinical trial, pure genistein supplementation (54 mg/day, P.O for one year) improved both cardiac function and left atrial remodeling in postmenopausal women with metabolic syndrome [138]
By microdosing, the body adjusts gradually, making the process more tolerable and sustainable
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