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More interestingly, several semimetallic nanomaterials, such as selenium (Se)- and tellurium (Te)-based nanoparticles, can also decrease intracellular GSH levels
The latest developed multifunctional nanoparticles have integrated functional modules such as anti-oxidation, anti-inflammation, and anti-apoptosis, which have significantly enhanced the synergistic therapeutic effect
Exposure to cadmium (Cd) and excess molybdenum (Mo) disrupts ovarian micronutrient balance, shifts the Th1/Th2 immune balance toward Th1, and activates ER stress, triggering ovarian necroptosis through the RIPK1/RIPK3/MLKL pathway, ultimately impairing ovarian function ( In conclusion, external factors such as environmental pollutants, immune system damage, and stress-induced OS can trigger necroptosis
coli , oxidants promote S-glutathionylation of the MarR repressor (a MarR-family protein), reducing its DNA binding and derepressing the mar operon (including acrAB )
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