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This is achieved by the carnitine-acylcarnitine translocase (CACT), which transports their carnitine-bound form (acylcarnitine)
Most side effects are gastrointestinal in nature and often occur when the dose is being increased
Recent studies have linked semaglutide, the most commonly prescribed GLP-1 receptor agonist, with increased incidents of the rare but vision-threatening complication of ischemic optic neuropathy
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