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Local rectal delivery in a gastrointestinal condition cannot be assumed to predict systemic exposure, tissue concentrations, effectiveness, or safety from an injection or oral product

It says gastric side effects are more pronounced during dose escalation, while stable maintenance doses allow more predictable absorption

The product does not cause irritation or breakouts on the skin

Importantly, Novo Nordisk is committed to ensuring responsible use of our medicines. If you are struggling with suicidal thoughts or are experiencing a mental health crisis and live in New York City, you can call 1-888-NYC-WELL for free and confidential crisis counseling