Physical changes like pale skin or a sore tongue, and digestive issues such as loss of appetite or constipation, may also be signs your body needs more B12
References: Gwyer, D., Wragg, N
Mechanistically, GHK-Cu has been shown to stimulate collagen and elastin synthesis in dermal fibroblasts, increase decorin (a small proteoglycan that helps regulate collagen organization), and influence matrix metalloproteinases and their inhibitors
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