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J Phys Chem A 119(24):62326243

Most of the product licences, or marketing authorities as they are called in the UK, for hydroxocobalamin date from the 1990s when the requirement for evidence was different than it is now

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Compliance Monitoring Implement strategies to monitor and ensure the subject's compliance with the prescribed dosage regimen, such as participant diaries, regular follow-up visits, and periodic assessments of the remaining spray volume