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In the pivotal MAESTRO-NASH of THR agonist Rezdiffra, steatohepatitis resolution was seen in 30% of patients on a 100mg dose, compared to 10% with placebo, after 52 weeks
Appetite changes are often noticed within the first 1 to 2 weeks, even at the starting dose of 0.25mg
The primary outcomes were percent change in body weight and change in the WOMAC pain score (scale 0 - 100, with higher scores meaning worse outcomes) at week 68
A new triple-action weekly jab for type 2 diabetes could significantly reduce blood sugar and body weight, according to phase 3 trial results
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