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Researchers have explored DSIP for possible effects on sleep regulation, stress response, pain signaling, endocrine function, and nervous system activity

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These measures help ensure that researchers receive a formulation with reproducible characteristics suitable for scientific investigation

In mouse models, dual agonism had superior efficacy for weight loss and glucose control compared to a GLP-1RA alone 9 , with additive effects of the GIPR proposed to act through signaling in beta cells 10 , alpha cells 11 , the CNS (central nervous system) 12,13 and adipocytes 14