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To conserve water, the body pulls fluid away from the tissues surrounding the eyes, causing them to appear hollow and sunken
253,255 Several other neurologically active non-hormonal medications have been found to be helpful for reducing hot flashes
There is no FDA-approved systemic estriol formulation for the treatment of menopausal symptoms
These medications work through multiple complementary mechanisms: Appetite Regulation: Activate receptors in brains appetite centers Reduce hunger signals Increase feelings of fullness Decrease food cravings Gastric Effects: Slow stomach emptying Prolong satiety after meals Reduce portion sizes naturally Metabolic Benefits: Improve insulin sensitivity Better blood sugar control Reduce inflammation Positive cardiovascular effects The combination of these effects produces weight loss 2-4x greater than older medications
