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Discovery of 2-vinyl-10H-phenothiazine derivatives as a class of ferroptosis inhibitors with minimal human Ether-a-go-go related gene (hERG) activity for the treatment of DOX-induced cardiomyopathy

Along with the traditional risks of DMARDS, people taking JAK inhibitors have the additional risk of developing blood clots within blood vessels

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Bile acids are also conjugated by a similar sequence of reactions involving a microsomal cholylCoA synthetase and a cytosolic enzyme bile acidCoA: amino acid acyltransferase (Falany et al., 1994)