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[75] [76] The exact mechanisms involved in the development of schizophrenia and depression are not entirely clear, but the bioactive folate, methyltetrahydrofolate (5-MTHF), a direct target of methyl donors such as S-adenosyl methionine (SAMe), recycles the inactive dihydrobiopterin (BH 2 ) into tetrahydrobiopterin (BH 4 ), the necessary cofactor in various steps of monoamine synthesis, including that of dopamine and serotonin

Because of this, using a pill form of the supplement creates an additional step for transferring the B12 into the bloodstream and can cause your body to absorb less of the vitamin

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Boosts collagen production for firmer, younger-looking skin