Abbreviations R/R DLBCL: Relapsed/Refractory Diffuse Large B-Cell Lymphoma R-CHOP: Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone ICIs: Immune Checkpoint Inhibitors PD-1: Programmed Cell Death Protein 1 PD-L1: Programmed Death-Ligand 1 ROS: Reactive Oxygen Species ER: Endoplasmic Reticulum ICD: Immunogenic Cell Death DAMPs: Damage-Associated Molecular Patterns CRT: Calreticulin HMGB1: High Mobility Group Box 1 ATP: Adenosine Triphosphate DCs: Dendritic Cells GSTs: Glutathione S-Transferases NBDHEX: 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol NAC: N-acetylcysteine MMP: Mitochondrial Membrane Potential WB: Western Blot IHC: Immunohistochemistry H&E: Hematoxylin and Eosin RNA-seq: RNA Sequencing BMDCs: Bone Marrow-Derived Dendritic Cells GzmB: Granzyme B IFN-: Interferon Gamma 4-PBA: 4-Phenylbutyric Acid References Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, et al

As it relates to weight loss in adrenal fatigue, exercise can help balance cortisol levels in the body, which can help with weight loss
Its now sometimes used in protein coffee recipes
These changes can create a gaunt or aged appearance