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TBIs are categorized based on severity as mild, moderate, and severe based on clinical parameters such as loss of consciousness, amnesia, neurological symptoms, and the findings from structural brain imaging, such as CT or MRI scans (Blyth and Bazarian, 2010)
The flow rate for each run started at 0.2 ml/min for 5 min, followed by a gradient starting at 0% B and increasing linearly to 100% B over the course of 45 min with a flow rate of 0.7 ml/min, followed by an isocratic gradient of 100% B for 17 min at 0.7 ml/min before equilibrating for 8 min at 0% B with a flow rate of 0.7 ml/min
Researchers using nasal spray for TB-500 may need proportionally higher doses compared to BPC-157 to achieve equivalent systemic levels relative to injection administration
