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Escalation means increasing the study dose over time to help researchers assess tolerability

Zepbound is prescribed to people with: A BMI of 30 or higher, or A BMI of 27 or higher with at least one weight-related condition, such as high blood pressure or high cholesterol It is also approved for obstructive sleep apnea (OSA) Mounjaro is prescribed to: Adults with type 2 diabetes to help manage their blood sugar levels Some clinicians also prescribe it off-label for weight loss with the same or similar BMI ranges