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This, in part, reflects the challenge and mistrust of the medical establishment, which worsened during the Covid pandemic, but was already showing strong signs of opposition by the wide adoption of supplements (with a very similar lack of supportive data on efficacy and safety) long before 2020
Those following a vegan or strict vegetarian lifestyle are at greater risk of deficiency and may benefit from regular B12 supplementation or injections
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Higher B12 has been associated with reduced kidney function in population data, particularly among individuals with higher homocysteine concentrations
