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These obstacles can be overcome by Dihexa, a synthetic, small molecule HGF mimetic that is orally bioavailable, metabolically stable, blood-brain barrier permeable, and inexpensive to synthesize (McCoy et al., 2013)
Phase II human trials of thymosin beta-4 (TB-500's parent molecule) have been conducted examining tissue repair rates, though detailed results remain limited in peer-reviewed literature
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