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Initial assessment typically includes 24-hour urinary free cortisol measurement, late-night salivary cortisol testing, or low-dose dexamethasone suppression testing to confirm hypercortisolism

In company-reported late-phase maintenance data, patients in SURMOUNT-MAINTAIN first lost weight on higher-dose Zepbound, then either continued the maximum tolerated dose or stepped down to 5 mg for a maintenance year

13 More than half of adults taking these medications reported having difficulty affording them