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Earlier GLP-1 medications like Liraglutide 3.0 mg (Saxenda) also delivered meaningful results, with an average weight loss of 18.5 pounds compared to 6.2 pounds for placebo over 56 weeks
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Lastly, the results of a very recent systematic review and network meta-analysis aimed to compare the effects of oral antidiabetic drugs in endocrine and metabolic profiles in patients with PCOS confirmed that metformin was more beneficial in reducing serum total testosterone, whereas GLP-1RA + metformin reduced FAI more effectively [24]
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