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Among these, liraglutide in the LEADER study, semaglutide in the SUSTAIN-6, albiglutide in the Harmony Outcomes, dulaglutide in the REWIND, and efpeglenatide in the AMPLITUDE-O exhibited significant beneficial effects on 3-point major adverse cardiac events (3P-MACE: death from CV disease, non-fatal myocardial infarction, and non-fatal stroke), the primary end point of each study, compared to the placebo group, respectively
For oral semaglutide in adults without diabetes, the following comparisons are based on studies investigating individual drugs, and differences in participant characteristics, study designs, and treatment durations should be noted
The effect of some antineoplastic agents on glutathione S-transferase from research-subject erythrocytes