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Common Side Effects Nausea, especially in the early weeks Bloating or mild digestive discomfort Reduced appetite to the point of under-eating Less Common but Important Risk of muscle loss if protein intake is low Gallbladder-related concerns in some individuals Potential nutrient gaps due to reduced food intake These effects often depend on dosage, individual tolerance, and how well lifestyle habits support the therapy

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Aliquots taken from methanol solution at each of the time points were concentrated in vacuo, mixed with water, and extracted with ethyl acetate

British Journal of Nutrition , 85 (S2), S109S113