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doi: 10.1038/s41598-017-00221-9 77 WuWJWolcottRMPruettSB

This process involves various pathogenesis mechanisms, such as pathological calcium signaling in pancreatic acinar cells, changes in pH, coexistence and autophagy, the cleavage of trypsinogen by the lysosomal hydrolytic enzyme tissue protease B to trypsin, and decreased activity of the pancreatic acinar cell trypsin inhibitor (11-13)

Clinical Update 6/15/2018 Mediterranean Diet Study Retracted A landmark study about the benefits of the Mediterranean Diet was retracted and republished this week

Notably, only mDC were shown to produce IL-12 and to exert anti-angiogenic functions in the TME, whereas pDC were shown to interact with the vasculature by secreting IL-8 and IFN- (90)