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found that T1 stimulated endothelial cell migration and angiogenesis in vitro and accelerated wound healing (including reepithelialization and collagen deposition) in an animal punch-wound model (Malinda et al., J Immunol 160(2):1001-1006)

Particularly, GLP-1 activates the AMPK signaling cascade by binding to skeletal muscle GLP-1R, thereby promoting mitochondrial biogenesis and enhancing mitochondrial function