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Exp Biol Med (Maywood)
demonstrated that the glucagon-like peptide-1 receptor (GLP-1R) agonist exendin-4 (EX-4) inhibits ROS production and MMP-9 activation by activating the Wnt/-catenin signaling pathway in a rat model of temporary middle cerebral artery occlusion
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Retatrutide is a triple agonist at three existing receptors: GLP-1 (glucagon-like peptide-1 receptor), GIP (glucose-dependent insulinotropic polypeptide receptor), and glucagon receptor
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