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Retatrutide is a synthetic peptide engineered to activate three separate receptor pathways that play important roles in metabolic and endocrine signalling: GLP-1 (Glucagon-Like Peptide-1) Receptors GIP (Glucose-Dependent Insulinotropic Polypeptide) Receptors Glucagon Receptors Unlike many traditional peptide compounds that focus on a single receptor target, Retatrutides triple-agonist activity enables researchers to investigate multiple biological pathways simultaneously