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Lower-dose treatment might one day suit certain patients, but she said, "Researchers need strong clinical trials first." She outlined what would have to come together: studies testing lower doses directly rather than in theory, proof that the results hold up over years without significant weight re-gain, a clearer picture of who benefits most, consistent manufacturing standards, and regulatory review of the evidence

Pro-inflammatory cytokines also increase G6PD expression in adipocytes

This article reflects information available in July 2026