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Cardiovasc Drugs Ther (2014) 28(5):42532.10.1007/s10557-014-6539-4 89 GonalvesAMarquesCLealERibeiroCFReisFAmbrsioAFet alDipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats
GLP-1 WT: 114.0 nM) (Fig
Early observational data and clinical experience suggest GLP-1s do not typically trigger or exacerbate ulcerative colitis flares, though individual gut microbiome composition and disease severity may influence tolerability and symptom response
That study will provide insights into the potential of GLP-1 RAs to modify the disease course in HFpEF patients
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