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This results in more targeted, potent effects with faster, more measurable improvements in performance metrics
Overall, the approach integrates rapid gelation for local retention with controlled release to dampen inflammation, facilitate MSC recruitment, and subsequently promote chondrogenic differentiation and matrix deposition
They are not intended to represent clinical evidence in humans, and AOD-9604 has not been approved by the FDA, EMA, or any other regulatory authority for any indication
10.1152/physrev.1986.66.2.469 108 WoeltjeK
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