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While no specific guidelines exist for MC4R -deficient patients, extrapolating from osteoporosis management principles suggests that baseline dual-energy X-ray absorptiometry (DXA) assessment may be reasonable in individuals with additional fracture risk factors or those anticipating substantial and sustained weight loss [72]

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Too slow If youre losing less than 0.5% body weight per week after the first month, consider: Whether youve reached an adequate dose Reviewing your dietary habits Checking for medication interactions Discussing with your prescriber about what dose is right for you Remember that NICE requires at least 5% weight loss by 6 months to continue treatment 6

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The indications for these drugs continue to expand, as researchers are testing whether theyll treat other illnesses

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