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Oral NSAIDs such as ibuprofen or naproxen may be appropriate for moderate pain when used at the lowest effective dose for the shortest duration necessary, particularly in patients without cardiovascular disease, kidney disease, or gastrointestinal risk factors

Human chimeric antigen receptor (CAR)-Tregs targeting OX40L for treatment of systemic lupus erythematosus [abstract]

Finally, a major objective along with efficacy is safety and, when compared with separate drugs functioning through a single mechanism, there is the promise of reduced toxicity through a less aggressive effect associated with any one single mechanism of action

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