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& Kasai, H
Prolonged UV exposure can induce matrix metalloproteinase-2 (MMP-2) and MMP-9 activation in basement membrane which can lead to collagen types 4 and 6 degradation and accumulation of more elastic fibers in melasma patients (Inomata et al., 2003)
PCOScharacterized by irregular periods, metabolic dysfunction, excess facial hair, and acnecan be tricky to diagnose and even tougher to treat
Peroxisomes also degrade hydrogen peroxide via catalase, peroxisomal dysfunction leads to ROS accumulation, exacerbating lipid peroxidation
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