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The short half-life of active GLP-1 and GLP-2 of only a few minutes due to rapid degradation by dipeptidyl peptidase-4 (DPP4) 12 suggests a rather dynamic regulation of these proteins

The bottom line There are many new weight-loss medications working their way through clinical trials and FDA approvals something many experts see as an overwhelmingly positive thing

This might involve starting with a small dose and working up to an ideal dose for the most effective rate of weight loss

Patients are advised to get a prescription from their doctor and to fill the prescription at a licensed pharmacy or use the FDA's BeSafeRx campaign to determine where to safely buy medications online