Antioxidants like GSH can prevent the harm that glucose and reactive oxygen species cause to -cells
MK-677 has a half-life of approximately 24 hours, allowing for once-daily oral dosing in research
Collectively, these findings highlight the role of carbohydrate metabolic pathways in sea urchins under nutrient-limited conditions, with evidence from other organisms indicating their involvement in regulating stress responses
Competing Interests Professor Melanie Davies has acted as a consultant/advisor and speaker for Eli Lilly, Novo Nordisk and Sanofi, has attended advisory boards for Abbvie, Amgen, AstraZeneca, Biomea Fusion, Carmot/Roche, Sanofi, Zealand Pharma Regeneron, GSK and EktaH and as a speaker for AstraZeneca and Boehringer Ingelheim