Seek medical advice if you develop: Signs of severe dehydration : Persistent vomiting or diarrhoea, reduced urine output, dizziness, or confusion Symptoms of hypoglycaemia : Tremor, sweating, confusion, palpitations, or loss of consciousness, especially if taking insulin or sulphonylureas concurrently Allergic reactions : Rash, itching, swelling of the face or throat, or difficulty breathing Visual changes : Blurred vision or other eye problems, which may indicate diabetic retinopathy changes requiring ophthalmology review Symptoms of gallbladder disease : Right upper quadrant pain, jaundice (yellowing of skin or eyes), or fever Regarding bad breath specifically, consult your healthcare provider if halitosis: Persists despite good oral hygiene and hydration Is accompanied by other concerning symptoms such as unexplained weight loss (beyond expected therapeutic effect), fever, or persistent cough Significantly impacts your quality of life or social functioning Is associated with a sweet, fruity odour (which may indicate diabetic ketoacidosis, particularly in insulin-treated patients or those taking SGLT2 inhibitors concurrently) Regular monitoring is an integral part of tirzepatide therapy

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You can also get blisters and sores: on your lips and in your mouth and throat this can make swallowing painful in the tube that carries pee out of your body this can cause pain when peeing on your eyes this can cause eye pain, pain when looking at bright lights and problems with your sight Other symptoms may include: diarrhoea and vomiting breathing problems such as wheezing Immediate action required: Call 999 or go to A&E if you or your child: have a rash spreading across the body, or a circular rash that's darker in the middle and lighter around the outside, after having an infection or starting a new medicine have a rash and the skin is itchy or painful, red, swollen, blistered or peeling are wheezing have tightness in the chest or throat are having trouble breathing or talking have a swollen or sore mouth, face, lips, tongue, throat or eyes These may be signs of a serious reaction like Stevens-Johnson syndrome and may need immediate treatment in hospital

Certain Medications Glutathione levels can drop when you take certain popular drugs, such as acetaminophen (paracetamol), antipsychotics, and some antibiotics