reported that tirzepatide treatment was associated with lower risk of all-cause mortality, adverse cardiovascular events, acute kidney injury, and adverse kidney events compared to GLP-1 RAs in patients with T2D [43]
Price and access will shape real-world impact
Back to Journals Drug Design, Development and Therapy Volume 19 A Comprehensive Review on the Pharmacokinetics and DrugDrug Interactions of Approved GLP-1 Receptor Agonists and a Dual GLP-1/GIP Receptor Agonist Authors Min JS, Jo SJ, Lee S, Kim DY, Kim DH, Lee CB , Bae SK Received 17 November 2024 Accepted for publication 14 April 2025 Published 30 April 2025 Volume 2025:19 Pages 35093537 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof
It mimics endogenous GLP-1, slowing gastric emptying, suppressing glucagon, and increasing glucose-dependent insulin secretion [5]