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Aging Cell , 20(2), e13314
Although its origin is still unknown, among the main causes related to long COVID (LC) are the persistence of chronic SARS-CoV-2 infection [33, 97,98,99,100,101,102,103,104,105], autoimmunity [106,107,108,109,110,111,112,113,114,115,116], chronic inflammatory state with immune alteration [110, 117,118,119,120,121,122,123,124,125,126,127], EpsteinBarr virus reactivation [128,129,130,131,132,133,134,135,136,137,138,139,140], hypocortisolism [128, 133, 141,142,143], or microclot formation [33, 144,145,146,147,148,149]
Oxidative stress or other conditions that deplete glutathione in the epithelium of the oral, nasal, and upper airway may, therefore, enhance susceptibility to influenza infection
CJC-1295 without DAC: Shorter half-life, requires more frequent dosing, but gives more control over timing
