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PlexusDx requires a recent gastroenterology evaluation and lab work before dispensing tirzepatide to patients with active Crohn's disease

Scheduling the injection on a day when you can control meal timing more carefully, or shifting the injection day to avoid social events with heavier eating, reduces the worst reflux episodes

You should actively rotate sites each week to prevent lipohypertrophy and ensure consistent absorption

GLP-1 receptor agonists should only be continued if there is an adequate response, defined as a reduction of at least 11 mmol/mol (1.0%) in HbA1c and a weight loss of at least 3% of initial body weight at six months