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This is an extension of the profile beyond local repair, towards the systemic regulation observed in models

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At the time, we had no idea what the mechanism might bea problem still unsolved even up until just to a few years ago, but then we finally figured it out: Vitamin B12 modulates the gene expression of the skin bacteria that cause acne

At optimal concentrations, GHK-Cu increases mRNA production for collagen types I and III, elastin, proteoglycans, and glycosaminoglycans, while laboratory studies show that topical application for 12 weeks improves collagen production in 70% of subjects compared to 50% with vitamin C and 40% with retinoic acid