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As mentioned, the current study showed that parkinsonian rats exhibited only a few GFAP-positive starshaped astrocytes scattered in the substantia nigra (Fig

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The indirect pathway involves activation of striatal dopamine 2 (D 2 ) dopamine receptors (which are coupled to a guanosine triphosphate-binding protein that opens potassium channels to hyperpolarize neurons, thereby reducing the excitability of the neuron)

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